COMPARATIVE STUDY AND MODELLING OF RUTIN EXTRACTION FROM HYPERICI HERBA AND HIPPOPHAES FRUCTUS

Abstract

The study on Rutin extraction from autochthonous Hyperici herba and Hippophaës fructus with methanol, ethanol and 1-propanol at different concentrations, temperatures and duration indicated that the most efficient solvent is 1-propanol, its optimum concentration being determined by the amount and type of the natural compounds from the two plants. Using the statistical analyzis and a factorial experiment of second order, two mathematical correlations between the Rutin extraction degree and the main parameters influencing the process (1-propanol concentration, temperature, duration) have been established. For both extraction systems, the considered variables control the extraction process in a 99.2–99.5% extent, the solvent concentration exhibiting the most important influence, especially for Rutin extraction from Hippophaës fructus.